Tobey Maguire

Spider-Man / Peter Parker

Kirsten Dunst

Mary Jane Watson

James Franco

New Goblin / Harry Osborn

Thomas Haden Church

Sandman / Flint Marko

Topher Grace

Venom / Eddie Brock

Bryce Dallas Howard

Gwen Stacy

Rosemary Harris

May Parker

J.K. Simmons

J. Jonah Jameson

James Cromwell

Captain Stacy

Dylan Baker

Dr. Curt Connors

Theresa Russell

Emma Marko

Bill Nunn

Joseph 'Robbie' Robertson

Bruce Campbell

Maître D'

Elizabeth Banks

Miss Brant

Ted Raimi

Hoffman

Perla Haney-Jardine

Penny Marko

Willem Dafoe

Green Goblin / Norman Osborn

Cliff Robertson

Ben Parker

Elya Baskin

Mr. Ditkovitch

Mageina Tovah

Ursula

John Paxton

Houseman

Becky Ann Baker

Mrs. Stacy

Stan Lee

Man in Times Square

Michael Papajohn

Dennis Carradine / Carjacker

Joe Manganiello

Flash Thompson

Hal Fishman

Anchorman

Lucy Gordon

Jennifer Dugan

Steve Valentine

Photographer

Tim Maculan

Play Director

Marc Vann

Play Producer

Joe Bays

Jazz Club Manager

Gregg Daniel

Precinct Detective

Rogelio T. Ramos

Emergency Room Doctor

Timothy Patrick Quill

Crane Operator

Menachem Mendel Boymelgreen

Kid in Times Square

Nasir Stewart

Kid in Times Square

Austin Hendrickson

Kid in Times Square

Taylor Hemhauser

Kid in Times Square

Kathryn Bryding

Woman Outside Theater

Joe Virzi

Police Detective

Bill E. Rogers

New Jersey State Policeman

Michael Alexander

New Jersey State Policeman

April Parker Jones

Test Site Technician

Edward Padilla

Test Site Technician

Robert Curtis Brown

Test Site Technician

Terrell Clayton

Test Site Technician

Carolyn Neff

Test Site Technician

Christina Cindrich

Test Site Technician

Sonya Maddox

ICU Nurse

Andre B. Blake

Crane Disaster Radio Policeman

Derrick 'Phoenix' Thomas

Cop at Crane Disaster

Jessi Collins

Mary Jane's Replacement

Michael McLaughlin

Boy at Key to the City Ceremony

Anne Gartlan

Councilwoman

Emilio Rivera

Policeman at Sand Truck

Keith Woulard

Policeman at Sand Truck

Reynaldo Gallegos

Armored Car Driver

Jim Coope

Newstand Patron

Dean Edwards

Newsstand Patron

Margaret Laney

Newsstand Patron

Toni Wynne

Congratulatory Woman at Daily Bugle

Aimee Miles

Coffee Shop Waitress

Tanya Bond

Jazz Club Waitress

Mark Kubr

Jazz Club Bouncer

Emma Raimi

Girl With Camera

Lorne Raimi

Boy at the Final Battle

Henry Raimi

Boy at the Final Battle

Samantha Ressler

Girl at the Final Battle

Alan Cohn

Jazz Club Musician

Dan Callahan

Jazz Club Musician

Daniel Cummings

Jazz Club Musician

Ron King

Jazz Club Musician

Carol Chaikin

Jazz Club Musician

Vance Hammond

Jazz Club Musician

Frank Anello

NYPD Officer (uncredited)

Anya Avaeva

Model (uncredited)

David Backus

Bucket Boy (uncredited)

Tony Besson

Photoshoot Client (uncredited)

Michael Ciesla

Photographer (uncredited)

Irina Costa

Jazz Club Waitress (uncredited)

John Crann

Theater Patron (uncredited)

Crystal Marie Denha

Jazz Club Girl (uncredited)

Amy V. Dewhurst

Columbia Grad Student (uncredited)

Keith Fausnaught

Pedestrian (uncredited)

Logan Fry

Automobile Driver (uncredited)

Tony Galtieri

News Spectator (uncredited)

Brian Hopson

News Reporter (uncredited)

Andrew James Jones

Jazz Club Bouncer (uncredited)

Natalie Jones

Girl at Key Ceremony (uncredited)

Christopher Jude

Student (uncredited)

Brittany Krall

ER Nurse (uncredited)

Pierangeli Llinas

Woman in Court (uncredited)

Bernadette Lords

British Publicist (uncredited)

Natalie McNeil

Girl Screaming in Camaro (uncredited)

Martha Millan

Oscorp Receptionist (uncredited)

Michele-Nanette Miller

Girl in Times Square (uncredited)

Claudia Katz Minnick

Robbie's Assistant (uncredited)

Jen Oda

Beautiful Girl (uncredited)

Anjelia Pelay

Beautiful Woman (uncredited)

Nick Poltoranin

Police Officer (uncredited)

Vanessa Reseland

Beautiful Woman (uncredited)

La Rivers

Beautiful Woman (uncredited)

Bria Roberts

Businesswoman (uncredited)

Vanessa Ross

Sandman Victim (uncredited)

Brenna Roth

Bad Girl (uncredited)

Shade Rupe

City Hall Cheerer (uncredited)

Abbey Skinner

Café Girl (uncredited)

Daniel Shafer

Jazz Club Guest (uncredited)

Kristin Somo

Jazz Club Patron (uncredited)

Jennifer Sparks

Jazz Club Waitress (uncredited)

Christopher Stadulis

NY Firefighter (uncredited)

Aija Terauda

Model (uncredited)

Evelyn Vaccaro

Beautiful Woman (uncredited)

Nick Vlassopoulos

Bar Patron #5 (uncredited)

Sincerely A. Ward

Model (uncredited)

Jennifer Weston

ER Nurse (uncredited)

Ray Wineteer

Spectator (uncredited)

Emily Eckes

Beautiful Woman (uncredited)

Craig 'Radio Man' Castaldo

Radioman (uncredited)

Claude Jay

Cop at the rescue if Mary Jane Watson